more>SIPCD Snapshots

Invited Speakers



Kinam Park

Kinam Park


Showalter Distinguished Professor & Professor of Industrial and Molecular Pharmaceutics

Weldon School of Biomedical Engineering

Purdue University, West Lafayette, IN

U.S.A.


Group Website: http://kinampark.com/


Kinam Park, Ph.D., joined the faculty of Purdue University in 1986 and became a full professor in 1994. He became the Showalter Distinguished Professor of Biomedical Engineering in 2006. He has studied drug delivery systems for more than four decades, focusing on the use of polymers for controlled drug release formulations, including oral delivery systems (fast-dissolving tablets, oral sustained release formulations, gastric retention devices, and hydrotropic polymers for delivery of poorly soluble drugs) and intravenous administration of poorly soluble drugs (polymer micelles and drug crystals). His recent research focuses on PLGA-based injectable, long-acting formulations for delivering small molecules, peptides, and protein drugs. He is currently developing 2~6-month long-acting naltrexone/buprenorphine injectable formulations for treating opioid use disorder. He founded Akina, Inc., specializing in biodegradable specialty polymers for drug delivery/biomaterials applications, and Midwest GMP for manufacturing Phase I clinical formulations.

 

Representative Publications

[1] Skidmore, S., Hadar, J., Garner, J., Park, H., Park, K., Wang, Y. and Jiang, X.J.: Complex sameness: Separation of mixed poly(lactide-co-glycolide)s based on the lactide:glycolide ratio, J. Control. Release, 300: 174-184, 2019.

[2] Park, K., Skidmore, S., Hadar, J., Garner, J., Park, H., Otte, A., Soh, B.K., Yoon, G., Yu, D., Yun, Y., Lee, B.K., Jiang, X.J. and Wang, Y.: Injectable, long-acting PLGA formulations: Analyzing PLGA and understanding microparticle formation, J. Control. Release, 304: 125-134, 2019.

 [3]  Bae, Y.H. and Park, K.: Advanced drug delivery 2020 and beyond: Perspectives on the future, Adv. Drug Del. Rev., 158: 4-16, 2020.

[4] Park, K., Otte, A., Sharifi, F., Garner, J., Skidmore, S., Park, H., Jhon, Y.K., Qin, B., and Wang. Y.: Formulation composition, manufacturing process, and characterization of poly(lactide-co-glycolide) microparticles, J. Control. Release, 329: 1150-1161, 2021.

[5] Otte, A., Damen, F., Goergen, C., and Park, K.: Coupling the in vivo performance to the in vitro characterization of PLGA microparticles, Int. J. Pharm., 604: 120738, 2021.

[6] Park, H., Otte, A., and Park, K.: Evolution of drug delivery systems: From 1950 to 2020 and beyond, J. Control. Release, 342: 53-65, 2022.

[7] Garner, J., Skidmore, S., Hadar, J., Park, H, Park, K., Otte, A., Jhon, Y.L., Xu, X., Qin, B., and Wang. Y.: Scanning analysis of sequential semi-solvent vapor impact (SAVI) to study naltrexone release from PLGA microparticles, Mol. Pharm., 19 (11): 4286-4298, 2022.

[8] Otte, A., Soh, B.K., and Park, K.: The impact of post-processing temperature on PLGA microparticle properties, Pharm. Res., 40: 2677-2685, 2023.

 



Soochow University Biomedical Polymers Laboratory, College of Chemistry, Chemical Engineering and Materials Science

College of Pharmaceutical Sciences, International College of Pharmaceutical Innovation

Soochow University, 199 Ren-Ai Road, Suzhou 215123, China