Lillian Barboul Thomas Professor, Purdue University

Department of Industrial and Molecular Pharmaceutics

USA

Group Website: https://www.yeolab.org/

Prof. Yoon Yeo is the Lillian Barboul Thomas Professor and Associate Department Head of Industrial and Molecular Pharmaceutics at Purdue University. She has built expertise in pharmaceutical sciences and drug delivery through Ph.D. training in protein microencapsulation and post-doc training in hydrogel-based biomaterials. At Purdue, Prof. Yeo leads a research program specializing in immunomodulatory formulations for anti-inflammatory applications and cancer immunotherapy, intracellular delivery of gene therapeutics and peptide antibiotics, new methods of delivering anticancer drugs, and long-acting drug delivery systems, with the support of the NIH, NSF, and industry. She has authored 130 peer-reviewed papers with an h-index of 61 and 13,000 citations. Prof. Yeo is a Fellow of the American Association of Pharmaceutical Scientists (AAPS, 2019) and the Controlled Release Society (CRS, 2022) and currently serves as a Deputy Editor-in-Chief of the Journal of Controlled Release and for the CRS Board of Directors (2023-2026). She received the NSF CAREER award (2011), New Investigator Awards from the AAPS (2009), and American Association of Colleges of Pharmacy (2008).

Representative Publications

1. Soonbum Kwon, Fanfei Meng, Hassan Tamam, Hytham Gadalla, Jianping Wang, Boyang Dong, Amber Hopf Jannasch, Timothy Ratliff, Yoon Yeo. Systemic delivery of paclitaxel by find-me nanoparticles activates anti-tumor immunity and eliminates tumors. ACS Nano. (2024) 18: 3681–3698.

2. Dhawal Chobisa, Anbukkarasi Muniyandi, Kamakshi Sishtla, Timothy W. Corson, Yoon Yeo. Long-Acting Microparticle Formulation of Griseofulvin for Ocular Neovascularization Therapy. Small. (2023): 2306479.

3. Fanfei Meng, Jianping Wang, Yanying He, Gregory M. Cresswell, Nadia A. Lanman, L. Tiffany Lyle, Timothy L. Ratliff, Yoon Yeo. A single local delivery of paclitaxel and nucleic acids via an immunoactive polymer eliminates tumors and induces antitumor immunity. PNAS. (2022) 119: e2122595119.

4. Simseok A. Yuk, Hyungjun Kim, Nader S. Abutaleb, Alexandra M. Dieterly, Maie S. Taha, Michael D. Tsifansky, L. Tiffany Lyle, Mohamed N. Seleem, Yoon Yeo. Nanocapsules modify membrane interaction of polymyxin B to enable safe systemic therapy of Gram-negative sepsis. Science Advances. (2021) 7: eabj1577.

5. Hyungjun Kim, Simseok A. Yuk, Alexandra M. Dieterly, Soonbum Kwon, Jinho Park, Fanfei Meng, Hytham H. Gadalla, Maria Jose Cadena, L. Tiffany Lyle, Yoon Yeo, Nanosac, a non-cationic and soft polyphenol nanocapsule, enables systemic delivery of siRNA to solid tumors. ACS Nano. (2021) 15(3): 4576–4593.

6. Fanfei Meng, Jianping Wang, Qineng Ping, Yoon Yeo. Quantitative Assessment of Nanoparticle Biodistribution by Fluorescence Imaging, Revisited. ACS Nano. (2018) 12: 6458–6468.