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Invited Speakers



Jan van Hest (Keynote Speaker)

Jan C.M. van Hest

 

Professor of Bio-organic Chemistry

Radboud University Nijmegen, Institute for Molecules and Materials

Heyendaalseweg 135, 6525 AJ Nijmegen

TheNetherlands

 

Group Website:

http://www.ru.nl/bio-orgchem/

 

 

Jan van Hest conducted his doctoral research at the Eindhoven University of Technology under supervision of Prof. Bert Meijer (Ph.D. 1996). As a postdoctoral researcher he worked with Prof. D. A. Tirrell, at the University of Massachusetts in Amherst. In 1997 he joined the chemical company DSM, where he worked as research scientist and later on as group leader on the development of innovative material concepts. In 2000 he was appointed as a full professor in bio-organic chemistry at the Radboud University Nijmegen. Jan van Hest is a VICI recipient (2010) and was a member of The Young Academy of the Royal Netherlands Academy of Arts and Sciences from 2005 to 2010.  He is a member of the research team that was awarded a gravitation program grant for Functional Molecular Systems in 2012. He is an associate editor of Bioconjugate Chemistry. 26 PhD students have graduated under supervision of van Hest and 18 PhD students are currently pursuing their doctorate. More than 270 papers have been published. He is co-inventor of 17 patents/patent applications and he is a cofounder of the start-up companies Encapson, FutureChemistry, Noviosense and Noviotech.

Research interests: 1. The design and synthesis of bio-inspired peptide-based materials; 2. The development of bioconjugation methods to construct biohybrid systems; 3. Compartmentalization approaches to create scaffolds and delivery vehicles for application in nanomedicine; 4. Adaptive nano- and micro-compartments that mimic cellular behavior.

Representative Publications

[1] S.F.M. van Dongen, W.P.R. Verdurmen, R.J.R.W. Peters, R.J.M. Nolte, R. Brock, J.C.M. van Hest, Cellular integration of an enzyme-loaded polymersome nanoreactor, Angew. Chem. Int. Ed. 40 (2010) 7213-7216

[2] J.V. Georgieva, R.P. Brinkhuis, K. Stojanov, C.A.G.M. Weijers, H. Zuilhof, F.P.J.T. Rutjes, D. Hoekstra, J.C.M. van Hest, I.S. Zuhorn, Peptide-mediated blood-brain barrier transport of polymersomes, Angew. Chem. Int. Ed. 33 (2012) 8339-8342.

[3] D.A. Wilson, R.J.M. Nolte, J.C.M. van Hest, Autonomous movement of platinum-loaded stomatocytes. Nat. Chem. 4 (2012) 268.

[4] R.J.R.W. Peters, M. Maguet, S. Marais, M.W. Fraaije, J.C.M. van Hest, S. Lecommandoux, Cascade reactions in multicompartmentalized polymersomes, Angew. Chem. Int. Ed. 53 (2014) 146-150.

      [5] R.J.R.W. Peters, M. Nijemeisland, J.C.M. van Hest, Reversibly triggered protein-ligand assemblies in giant vesicles, Angew. Chem. Int.         Ed. 54 (2015) 9614-9617.


Soochow University Biomedical Polymers Laboratory 
199 Ren-Ai Road, Suzhou Industrial Park, Suzhou 215123, China