Hai-Quan Mao, Ph.D.
Associate Director, Institute of NanoBioTechnology
Professor, Department of Materials Science and Engineering, Whiting School of Engineering; Department of Biomedical Engineering and Translational Tissue Engineering Center, School of Medicine;
Johns Hopkins University
Dr. Mao received his Ph.D. (1993) in Polymer Chemistry from Wuhan University in China, and completed his postdoc training in Biomedical Engineering at Johns Hopkins University from 1995 to 1998. After a short tenure at Johns Hopkins in Singapore as a co-principal investigator from 1999 to 2003, he joined Johns Hopkins University as an Assistant Professor in 2003 and was promoted to Associate Professor with tenure in 2009, and to full Professor in 2013 in the Departments of Materials Science and Engineering and Biomedical Engineering. He has been a founding member of the Johns Hopkins Institute for NanoBioTechnology (INBT) and the Translational Tissue Engineering Center (TTEC) at Johns Hopkins School of Medicine. He now serves as the Associate Director of INBT. Dr. Mao has held guest professorship in Wuhan University (1999), National Univeristy of Singapore (2001), Wuhan Univeeristy of Science and Technology (2005), and Sun Yat-sen University (2013). Dr. Mao's research focuses on engineering nanomaterials for regenerative medicine and therapy delivery applications. He has authored 135 peer-reviewed articles and is an inventor of 22 issued US patents. His work has collected more than 11,960 citations with an h-index of 54. He was the recipient of the Young Investigator Award at National University of Singapore in 2002, the National Science Foundation Faculty CAREER Award in 2008 for his work on artificial matrix for stem cell engineering. He was elected Fellow of Royal Society of Chemistry in 2014, member of the National Academy of Inventors in 2015, and Fellow of the American Institue of Medical and Biological Engineeering (2018). He currently serves as an associate editor for Biomaterials, and on the Editorial Advisory Boards of Journal of Materials Chemistry B and ACS Biomaterials Science and Engineering.
. Roy K, Mao HQ, Huang SK, Leong KW. Oral gene delivery with chitosan-DNA nanoparticles generates immunologic protection in a murine model of peanut allergy. Nat. Med. 5(4): 387-391 (1999).
. Mao HQ, Roy K, Troung-Le VL, Janes KA, Lin KY, Wang Y, August JT, Leong KW. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. J. Control. Release. 70(3): 399-421 (2001).
. Christopherson GT, Song H, Mao HQ. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials. 30(4): 556-564 (2009).
. Jiang X, Qu W, Pan D, Ren Y, Williford JM, Cui H, Luijten E, Mao HQ. Plasmid-templated shape control of condensed DNA-block copolymer nanoparticles. Adv. Mater. 25(2): 227-232 (2013)
. Santos JL, Mao HQ, et al. Continuous production of discrete plasmid DNA-polycation nanoparticles using flash nanocomplexation. Small. 12(45): 6214-6222 (2016).
. He Z, Mao HQ, et al. Scalable fabrication of size-controlled chitosan nanoparticles for oral delivery of insulin. Biomaterials. 130: 28–41 (2017).
. Hickey JW, Mao HQ, et al. Biologically inspired design of nanoparticle artificial antigen-presenting cells for immunomodulation. Nano Lett. 17(11): 7045-7054 (2017).