Invited Speakers
Kanjiro Miyata
Kanjiro Miyata
Associate Professor, Department of Materials Engineering, Graduate School of Engineering, The University of Tokyo
Group Website:
http://www.bmm.t.u-tokyo.ac.jp/english/index.html
Dr. Kanjiro Miyata received his Ph.D. (2006) in Department of Materials Engineering from The University of Tokyo. He started his academic career as project Assistant Professor (2006) at Department of Bioengineering, Graduate School of Engineering, The University of Tokyo. He moved to Center for Disease Biology and Integrative Medicine, Graduate School of Medicine, The University of Tokyo as Assistant Professor in 2009 and was promoted to Associate Professor in 2013. He then returned to Department of Materials Engineering, The University of Tokyo in 2016 as a PI. He has received several scientific awards, including Award for Encouragement of Research in Polymer Science from The Society of Polymer Science, Japan (2009), Award for Young Investigator of Japanease Society for Biomaterials from Japanese Society for Biomaterials (2012), 7th Award for Encouragement of Research in The Japan Society of Drug Delivery System from The Japan Society of Drug Delivery System (2015), 2014 DDTR Outstanding Research Paper Award from Controlled Release Society (2015), 2017 The Nucleic Acids Therapeutics Society of Japan Award for Young Scientists from Nucleic Acids Therapeutics Society of Japan (2017) and Nano Research Young Innovator Awards in NanoBiotech 2018 (2018). He is a member of the Councils of The Japan Society of Drug Delivery System (from 2013), Nucleic Acids Therapeutics Society of Japan (from 2015), Japanese Society for Biomaterials (from 2015), The Japan Society of Nucleic Acids Chemistry (from 2016) and Nano Biomedical Society (from 2018). His current major research interest is the development of smart nanomaterials aimed at drug and oligonucleotide delivery.
Representative Publications
[1] H. J. Kim, S. Ogura, T. Otabe, R. Kamegawa, M. Sato, K. Kataoka, K. Miyata, Fine-tuning of hydrophobicity in amphiphilic polyaspartamide derivatives for rapid and transient expression of messenger RNA directed toward genome engineering in brain. ACS Cent. Sci. in press.
[2] S. Watanabe, K. Hayashi, K. Toh, H. J. Kim, X. Liu, H. Chaya, S. Fukushima, K. Katsushima, Y. Kondo, S. Uchida, S. Ogura, T. Nomoto, H. Takemoto, H. Cabral, H. Kinoh, H. Tanaka, M. R. Kano, Y. Matsumoto, H. Fukuhara, S. Uchida, M. Nangaku, K. Osada, N. Nishiyama, K. Miyata, K. Kataoka, In vivo rendezvous of small nucleic acid drugs with charge-matched block catiomers to target cancer. Nat. Commun. 10, 1894 (2019).
[3] B. S. Kim, S. Chuanoi, T. Suma, Y. Anraku, K. Hayashi, M. Naito, H. J. Kim, I. C. Kwon, K. Miyata, A. Kishimura, K. Kataoka, Self-assembly of siRNA/PEG-b-catiomer at integer molar ratio into 100 nm-sized vesicular polyion complexes (siRNAsomes) for RNAi and codelivery of cargo macromolecules. J. Am. Chem. Soc. 141, 3699–3709 (2019).
[4] Y. Anraku, H. Kuwahara, Y. Fukusato, A. Mizoguchi, T. Ishii, K. Nitta, Y. Matsumoto, K. Toh, K. Miyata, S. Uchida, K. Nishina, K. Osada, K. Itaka, N. Nishiyama, H. Mizusawa, T. Yamasoba, T. Yokota, K. Kataoka, Glycaemic control boosts glucosylated nanocarrier crossing the BBB into the brain. Nat. Commun. 8, 1001 (2017).
[5] K. Katsushima, A. Natsume, F. Ohta, K. Shinjo, A. Hatanaka, N. Ichimura, S. Sato, S. Takahashi, H. Kimura, Y. Totoki, T. Shibata, M. Naito, H. J. Kim, K. Miyata, K. Kataoka, Y. Kondo, Targeting the notch-regulated non-coding RNA TUG1 for glioma treatment. Nat. Commun. 7, 13616 (2016).